VIP

VIP (Vasoactive Intestinal Peptide) | Peptide Complex

Neuropeptide

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide found throughout the central and peripheral nervous system, as well as the gastrointestinal tract. It acts as both a neurotransmitter and a hormone, playing a diverse role in immune regulation, circadian rhythm, vasodilation, and gut motility. VIP has attracted significant research interest due to its potent anti-inflammatory and neuroprotective properties.

• Anti-Inflammatory Activity — VIP has demonstrated strong immunomodulatory effects, suppressing pro-inflammatory cytokines including TNF-α, IL-6, and IL-12 while upregulating anti-inflammatory mediators.

• Neuroprotection — Research indicates VIP promotes neuronal survival, reduces neuroinflammation, and may play a protective role in neurodegenerative disease models.

• Circadian Rhythm Regulation — VIP is a key signaling molecule in the suprachiasmatic nucleus, playing a central role in the synchronization of the body's internal clock.

• Gut Health — As a gastrointestinal neuropeptide, VIP regulates smooth muscle relaxation, intestinal secretion, and mucosal immune function.

• Vasodilation & Pulmonary Function — Studies indicate VIP promotes vasodilation and bronchodilation, with interest in its application to pulmonary hypertension and respiratory research.